Plan, book, travel with confidence
Better together
Save up to $1,045 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Your Sant'Antioco Island Vacation

Make planning your next epic adventure effortless with a Sant'Antioco Island vacation package. If it's coastal beaches, views and history you're after, you won't be disappointed. During your trip to Sant'Antioco Island, you'll want to get around to a few of its top cities. What shouldn't you miss? Calasetta. Expedia has hotels, flights, car rentals and more to help you create your very own tailored Sant'Antioco Island vacation today.

The Latest Sant'Antioco Island vacation packages

Price found within the past 48 hours. Click for updated prices.

Miramare Cagliari Hotel Museo

Marina District

$1,633

per person

Mar 14 - Mar 16

found 11 hours ago

Roundtrip flight included

New York (NYC) to Cagliari (CAG)

8.4/10 Very Good! (294 reviews)

Amazing back in time

Reviewed on Sep 7, 2025

Forte Village Resort - Il Castello

$2,442

per person

Mar 14 - Mar 16

found 11 hours ago

Roundtrip flight included

New York (NYC) to Cagliari (CAG)

8/10 Very Good! (7 reviews)

Hotel Palazzo Doglio

Bonaria

$1,767

per person

Mar 14 - Mar 16

found 11 hours ago

Roundtrip flight included

New York (NYC) to Cagliari (CAG)

9.6/10 Exceptional! (304 reviews)

Very nice hotel with excellent staff who went above and beyond to help make our stay relaxing and enjoyable. We were there in December, and there were beautiful decorations and a Christmas market in the courtyard. Several excellent restaurants on the property, and lots more a short walk away. Our room was spotless. Very large and well appointed.

Reviewed on Dec 19, 2025

Residenza d'Epoca Regina d'Arborea

$1,727

per person

Mar 14 - Mar 16

found 11 hours ago

Roundtrip flight included

New York (NYC) to Cagliari (CAG)

9.2/10 Wonderful! (35 reviews)

Lovely stay and staff were very helpful and courteous. Bathroom fixtures and fittings could have done with an upgrade.

Reviewed on Nov 10, 2025

Caesar's Hotel

$1,675

per person

Mar 14 - Mar 16

found 11 hours ago

Roundtrip flight included

New York (NYC) to Cagliari (CAG)

8.4/10 Very Good! (209 reviews)

Excellent breakfast. Nice hotel, with free parking. Close to the salt marshes, great area for birdwatching.

Reviewed on Oct 24, 2025

Don't see what you're looking for?

See all available trips from Columbus to Sant'Antioco Island

View all trips

Discover the most popular places to visit in Sant'Antioco Island

An island Sant’Antioco where already beauty reigns Sardegna will always be full of beautiful nature to discover and am discovering it.

Maladroxia Beach

If a restful vacation is part of your travel plans, Maladroxia Beach might be the perfect place to seek out during your trip to Maladroscia.

Calasetta Marina

Explore the waterfront in Calasetta with a trip to Calasetta Marina. While you're in the area, stroll along the beaches.

Former Capo Sperone Signal Station

You can learn about the history of Capo Sperone with a visit to Former Capo Sperone Signal Station. Stroll along the beaches or visit the monuments while you're in the area.

What to do in Sant'Antioco Island

From Calasetta: Scooter hire on the island of Sant'Antioco

$76

per adult

See all activities in Sant'Antioco Island

Sant'Antioco Island Hotel Deals

Nea Villa, for 11 people, swimming pool, panoramic terrace, 70 mt from the beach

sant'antioco

10/10 Exceptional! (60 reviews)

We had an incredible 4 weeks in this property with friends and family, including babies and children. The location and view are just amazing. The owner was incredibly helpful and arrange periodic cleaning and fresh linens. I can highly recommend it and would love to return. The views from the roof ...

Reviewed on Sep 30, 2025

Get rates

apartment with pine forest

Calasetta

La Pineta

La casa e' esattamente come nelle foto. E' fornita di tutti i confort necessari come WIFI, Tv, Lavatrice (un po vecchia ma funziona), scaldabagno, parcheggio macchina, frigorifero e tutto cio che serve in cucina. Zona molto tranquilla a 15 minuti di macchina dal centro dal paese. 10 min a piedi dalla ...

Reviewed on Jul 20, 2021

Get rates

Tenuta Blancamar

Localià Cannai Crisionis Sant'Antioco SU

9.8/10 Exceptional! (7 reviews)

Great stay. Friendly owners!

Reviewed on Aug 8, 2023

Get rates

See all 926 properties in Sant'Antioco Island

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.