Sant'Antioco Island Vacations from $1,059
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $1,045 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Sant'Antioco Island Vacation
Make planning your next epic adventure effortless with a Sant'Antioco Island vacation package. If it's coastal beaches, views and history you're after, you won't be disappointed. During your trip to Sant'Antioco Island, you'll want to get around to a few of its top cities. What shouldn't you miss? Calasetta. Expedia has hotels, flights, car rentals and more to help you create your very own tailored Sant'Antioco Island vacation today.
The Latest Sant'Antioco Island vacation packages
Price found within the past 48 hours. Click for updated prices.
Don't see what you're looking for?
See all available trips from Columbus to Sant'Antioco Island
View all tripsDiscover the most popular places to visit in Sant'Antioco Island
Maladroxia Beach
If a restful vacation is part of your travel plans, Maladroxia Beach might be the perfect place to seek out during your trip to Maladroscia.
Forte Su Pisu
You can find out about the history of Sant'Antioco when you stop by Forte Su Pisu. While you're in the area, stroll along the beaches.
Hypogeum Village
You can find out about the history of Sant'Antioco with a visit to Hypogeum Village. While you're in the area, stroll along the beaches.
What to do in Sant'Antioco Island
From Calasetta: Scooter hire on the island of Sant'Antioco
$62
per adult
Sant'Antioco: Guided E-Bike Excursion at Sunset
$58
per adult
Sant'Antioco Island Hotel Deals
MuMA Hostel
Lungomare Colombo 25 Sant'Antioco SU
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $92 total per night from Apr 19 to Apr 20
$92 total
Apr 19 - Apr 20
Total with taxes and fees
9.2/10 Wonderful! (139 reviews)
Bien situé, bon service, mauvaise climatisation
Reviewed on Oct 26, 2025
Lu’ Hotel Maladroxia
Via Golfo di Palmas Sant'Antioco SU
$99 nightly
The price is $118 total per night from Apr 24 to Apr 25
$118 total
Apr 24 - Apr 25
Total with taxes and fees
8.6/10 Excellent! (101 reviews)
Beautiful location. We had a fantastic premium room with balcony. Hotel had robes, slippers and all the bathroom amenities needed. Solid breakfast choices. Staff was friendly overall. Marco checked us in, gave some great suggestions for dinner and beaches and walked us to our room. He exudes 4 star ...
Reviewed on Sep 21, 2025
Hotel Cala di Seta
Via Regina Margherita Calasetta SU
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $75 total per night from Apr 26 to Apr 27
$75 total
Apr 26 - Apr 27
Total with taxes and fees
8.8/10 Excellent! (67 reviews)
We had a great time Took the ferry to califorte
Reviewed on Oct 19, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Sant'Antioco Island Vacation Packages
SantAntioco Island Essential Information
Language | Italian |
|---|---|
Currency | Euros |
Local Welcome | Ciao |
Local Goodbye | Ciao |
Closest Airport | Elmas Airport (CAG) |
More vacations you might like
Explore a world of travel with Expedia
- Hotels near Forte Su Pisu
- Sant'antioco Hotels
- Hotels with a Pool in Sant'Antioco
- Hotels near Cala Sapone
- Spiaggia Grande Hotels
- Canai Hotels
- Hotels near Punta Trettu
- Calasetta Hotels
- Villas in Calasetta
- Apartments in Calasetta
- Historic Hotels in Calasetta
- B&B in Calasetta
- Hotels with Free Parking in Calasetta
- Hotels near Former Capo Sperone Signal Station
- Capo Sperone Hotels
- Hotels near La Bobba Beach
- San Giovanni Suergiu Hotels
- Carloforte Hotels
- Gay friendly Hotels in Carloforte
- Hotels with Tennis Courts in Carloforte
- Beach Hotels in Carloforte
- Villas in Carloforte
- Hotels with Free Parking in Carloforte
- Apartments in Carloforte
- 4 Star Hotels in Carloforte
- 5 Star Hotels in Carloforte
- Extended Stay Hotels in Carloforte
- Town Houses in Porto Botte
- Rv Parks in Porto Botte
- Porto Botte Hotels
- Hotels near Carbonia Serbariu Station
- San Pietro Island Hotels
- Winery Hotels in San Pietro Island
- Hotels near Palazzetto dello Sport
- Hotels near Piazza Roma
- Tratalias Hotels
- Portoscuso Hotels
- Gay friendly Hotels in Portoscuso
- Apartments in Portoscuso
- Hotel Wedding Venues Hotels in Portoscuso
- Forte Su Pisu
- Hypogeum Village
- Ferruccio Barreca Archeological Museum
- Visit Sant'Antioco
- Visit Cussorgia
- Spiaggia Grande Vacations
- Visit Spiaggia Grande
- Canai Vacations
- Visit Canai
- Visit Maladroscia
- Punta Trettu
- Calasetta Vacations
- Sottotorre Beach
- Visit Calasetta
- Church of San Maurizio
- Former Capo Sperone Signal Station
- Visit Capo Sperone
- San Pietro Beach
- La Bobba Beach
- Le Colonne di Carloforte
- Visit San Giovanni Suergiu
- Carloforte Vacations
- Visit Carloforte
- Visit Porto Botte
- Church of Santa Maria di Monserrato
- San Pietro Island Vacations
- Visit San Pietro Island
- Palazzetto dello Sport
- Piazza Marmilla
- Piazza Roma
- Visit Tratalias
- Visit Portoscuso
- Cala Lunga Beach
- Portoscuso Spanish Tower
- Visit Porto Pinetto
- Portopaglietto Beach
- Visit Sulcis Iglesiente
- Car rentals near Forte Su Pisu
- Car rentals near Sant'Antioco
- Car rentals near Spiaggia Grande
- Car rentals near Calasetta
- Hertz Rental Cars in Calasetta
- Car rentals near Calasetta Marina
- Car rentals near Carloforte
- Car rentals near Porto Botte
- Car rentals near Tratalias
- Car rentals near Portoscuso
- Europcar Rental Cars in Portoscuso
- Hertz Rental Cars in Portoscuso
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
